GeneReviews [Internet]
One of the main ways that progressive tubular and interstitial fibrosis occurs is through apoptotic death and the buildup of ECM (37, 38)
One study found that a 2% concentration of a glutathione cream improved the melanin index (a measure of melanin in skin) on dark spots when used twice a day for 10 weeks
Pinealon Pinealon is a tripeptide thought to influence neuronal metabolism and support mitochondrial function, especially in aging or stressed neural tissues
PMID: 37311055
Apart from visual problems, i.e., retinitis pigmentosa and/or optic atrophy, and hearing loss, this cohort of 13 unrelated patients also had other clinical features such as hypotonia, global developmental delay, axonal sensorimotor polyneuropathy, regression after febrile illness, ataxia, failure to thrive, progressive microcephaly, and encephalopathy [85]